DPPA2 Gene Summary [Human]
Predicted to enable chromatin binding activity. Predicted to be involved in system development. Predicted to act upstream of or within several processes, including lung-associated mesenchyme development; positive regulation of stem cell proliferation; and regulation of histone methylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | DPPA2 |
| Official Name | developmental pluripotency associated 2 [Source:HGNC Symbol;Acc:HGNC:19197] |
| Ensembl ID | ENSG00000163530 |
| Bio databases IDs | |
| Aliases | developmental pluripotency associated 2, cancer/testis antigen 100 |
| Synonyms | 2410088E07Rik, C80932, CT100, D19Mgi18, developmental pluripotency-associated 2, ECAT15-2, LOC151871, PESCRG1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DPPA2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SAP motif
- Dppa2/4 conserved region in higher vertebrates
- chromatin binding
- protein binding
- Dppa2/4 conserved region
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- premature ovarian failure
role in cell
- expression in
- maintenance
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DPPA2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- system development
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- chromatin binding