THOC7 Gene Summary [Human]
Predicted to enable RNA binding activity. Involved in mRNA export from nucleus and viral mRNA export from host cell nucleus. Located in cytosol and nuclear speck. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | THOC7 |
| Official Name | THO complex 7 [Source:HGNC Symbol;Acc:HGNC:29874] |
| Ensembl ID | ENSG00000163634 |
| Bio databases IDs | |
| Aliases | THO complex 7, Ngg1 interacting factor 3 like 1 binding protein 1, functional spliceosome-associated protein 24 |
| Synonyms | 1500006O09RIK, FLJ23445, fSAP24, hTREX30, NIF3L1BP1, RGD1305475, THO complex 7, THO complex subunit 7, TREX30 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human THOC7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Tho complex subunit 7
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- cytosol
- spliceosomes
- nucleoplasm
- nuclear speckles
- telomeres
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human THOC7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mRNA export from nucleus
- RNA splicing
- mRNA processing
Cellular Component
Where in the cell the gene product is active
- chromosome, telomeric region
- nucleus
- cytoplasm
- nuclear speck
- cytosol
- THO complex
- THO complex part of transcription export complex
- transcription export complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding