TASOR Gene Summary [Human]
Enables chromatin binding activity. Involved in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; protein localization to heterochromatin; and regulation of gene expression. Located in heterochromatin and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | TASOR |
| Official Name | transcription activation suppressor [Source:HGNC Symbol;Acc:HGNC:30314] |
| Ensembl ID | ENSG00000163946 |
| Bio databases IDs | |
| Aliases | transcription activation suppressor, transgene activation suppressor |
| Synonyms | 4732418E12, 4933409E02Rik, C3orf63, D14Abb1e, FAM208A, LOC102548123, LOC680168, MommeD6, RAP140, SE89-1, TASOR1, transcription activation suppressor |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TASOR often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein of unknown function (DUF3715)
- chromatin binding
- protein binding
Pathways
Biological processes and signaling networks where the TASOR gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- heterochromatin
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TASOR gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mesodermal to mesenchymal transition involved in gastrulation
- negative regulation of gene expression, epigenetic
- negative regulation of retroviral genome replication
- anterior/posterior axis specification, embryo
- positive regulation of methylation-dependent chromatin silencing
Cellular Component
Where in the cell the gene product is active
- heterochromatin
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- chromatin binding