CALHM4 Gene Summary [Human]

Predicted to enable cation channel activity. Predicted to be involved in cation transmembrane transport. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
CALHM4
Official Name
calcium homeostasis modulator family member 4 [Source:HGNC Symbol;Acc:HGNC:21094]
Ensembl ID
ENSG00000164451
Bio databases IDs NCBI: 221301 Ensembl: ENSG00000164451
Aliases calcium homeostasis modulator family member 4
Synonyms 4732454E20Rik, C6orf78, calcium homeostasis modulator family member 4, FAM26D, Gm643
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CALHM4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Calcium homeostasis modulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • adenoma formation
  • androgenic alopecia
  • aldosterone producing adrenocortical adenoma

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CALHM4 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • cation channel activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.