SBSPON Gene Summary [Human]
Predicted to be an extracellular matrix structural constituent. Colocalizes with collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SBSPON |
| Official Name | somatomedin B and thrombospondin type 1 domain containing [Source:HGNC Symbol;Acc:HGNC:30362] |
| Ensembl ID | ENSG00000164764 |
| Bio databases IDs | |
| Aliases | somatomedin B and thrombospondin type 1 domain containing, RPE spondin, rpe-spondin |
| Synonyms | C8orf84, Gm106, RGD1559717, RPESP, somatomedin B and thrombospondin type 1 domain containing, somatomedin B and thrombospondin, type 1 domain containing |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SBSPON often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Spondin-like TSP1 domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- lung adenocarcinoma
- polycystic kidney disease
- Crohn disease
- lung adenocarcinoma formation
- serous ovarian adenocarcinoma
- serous ovarian cancer
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
- vertigo
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SBSPON gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- extracellular matrix structural constituent