ZNF609 Gene Summary [Human]

Predicted to enable promoter-specific chromatin binding activity. Involved in regulation of myoblast proliferation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
ZNF609
Official Name
zinc finger protein 609 [Source:HGNC Symbol;Acc:HGNC:29003]
Ensembl ID
ENSG00000180357
Bio databases IDs NCBI: 23060 Ensembl: ENSG00000180357
Aliases zinc finger protein 609
Synonyms 9830165N24, LOC315766, mKIAA0295, RGD1561651, Zfp609, zinc finger protein 609
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF609 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RNA polymerase II transcription factor activity, sequence-specific DNA binding
  • chromatin binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • neuroticism
regulated by
regulates
  • DNA promoter
  • DNA endogenous promoter
  • RNA polymerase II
role in cell
  • proliferation
  • differentiation
  • migration by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZNF609 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • muscle organ development
  • regulation of myoblast proliferation
  • positive regulation of transcription from RNA polymerase II promoter
  • positive regulation of neuron migration
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • metal ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.