CARD19 Gene Summary [Human]
Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CARD19 |
| Official Name | caspase recruitment domain family member 19 [Source:HGNC Symbol;Acc:HGNC:28148] |
| Ensembl ID | ENSG00000165233 |
| Bio databases IDs | |
| Aliases | caspase recruitment domain family member 19, Bcl10-interacting protein with CARD |
| Synonyms | 1110007C09Rik, BinCARD, C9orf89, caspase recruitment domain family member 19, caspase recruitment domain family, member 19, RGD1306058 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CARD19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Death Domain Superfamily of protein-protein interaction domains
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CARD19 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of I-kappaB kinase/NF-kappaB cascade
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- nucleus
- mitochondrial membrane
- mitochondrion
- cytosol
Molecular Function
What the gene product does at the molecular level
- CARD domain binding