DPCD Gene Summary [Human]
This gene in mouse encodes a protein that may be involved in the generation and maintenance of ciliated cells. In mouse, expression of this gene increases during ciliated cell differentiation, and disruption of this gene has been linked to primary ciliary dyskinesia. [provided by RefSeq, Jul 2016]
Details
| Type | Processed Transcript |
| Official Symbol | DPCD |
| Official Name | deleted in primary ciliary dyskinesia homolog (mouse) [Source:HGNC Symbol;Acc:HGNC:24542] |
| Ensembl ID | ENSG00000166171 |
| Bio databases IDs | |
| Aliases | deleted in primary ciliary dyskinesia homolog (mouse) |
| Synonyms | deleted in primary ciliary dyskinesia, deleted in primary ciliary dyskinesia homolog (mouse), Gm17018, NDAC, RGD1307648 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DPCD often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DPCD protein family
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DPCD gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lateral ventricle development
- sperm motility
- spermatogenesis
- epithelial cilium movement
- third ventricle development
- establishment of localization in cell
- determination of left/right symmetry
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding