Gm17018 Gene Summary [Mouse]
Acts upstream of or within several processes, including epithelial cilium movement involved in extracellular fluid movement; flagellated sperm motility; and ventricular system development. Predicted to be located in extracellular region. Used to study hydrocephalus and primary ciliary dyskinesia. Orthologous to human DPCD (deleted in primary ciliary dyskinesia homolog (mouse)). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gm17018 |
| Official Name | predicted gene 17018 [Source:MGI Symbol;Acc:MGI:4820566] |
| Ensembl ID | ENSMUSG00000041035 |
| Bio databases IDs | |
| Aliases | predicted gene 17018 |
| Synonyms | deleted in primary ciliary dyskinesia, deleted in primary ciliary dyskinesia homolog (mouse), Gm17018, NDAC, RGD1307648 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gm17018 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DPCD protein family
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gm17018 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lateral ventricle development
- sperm motility
- spermatogenesis
- epithelial cilium movement
- third ventricle development
- establishment of localization in cell
- determination of left/right symmetry
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding