NUDT13 Gene Summary [Human]
Predicted to enable NADH pyrophosphatase activity. Predicted to be involved in NADH metabolic process and NADP catabolic process. Predicted to be located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | NUDT13 |
| Official Name | nudix hydrolase 13 [Source:HGNC Symbol;Acc:HGNC:18827] |
| Ensembl ID | ENSG00000166321 |
| Bio databases IDs | |
| Aliases | nudix hydrolase 13 |
| Synonyms | 4933433B15RIK, nudix hydrolase 13 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NUDT13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- NADH pyrophosphatase zinc ribbon domain
- NADH pyrophosphatase-like rudimentary NUDIX domain
- NUDIX domain
- pyrophosphatase
- nucleotide diphosphatase
- enzyme
- NUDIX hydrolase superfamily
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NUDT13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- NADH metabolic process
- nucleobase-containing small molecule interconversion
- NADP catabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- NAD+ diphosphatase activity
- NADH pyrophosphatase activity
- metal ion binding
- pyrophosphatase activity