Nudt13 Gene Summary [Rat]

Predicted to enable NADH pyrophosphatase activity. Predicted to be involved in NADH metabolic process and NADP catabolic process. Predicted to be located in mitochondrion. Orthologous to human NUDT13 (nudix hydrolase 13). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Nudt13
Official Name
nudix hydrolase 13 [Source:RGD Symbol;Acc:1592767]
Ensembl ID
ENSRNOG00000048195
Bio databases IDs NCBI: 682978 Ensembl: ENSRNOG00000048195
Aliases nudix hydrolase 13
Synonyms 4933433B15RIK, nudix hydrolase 13
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nudt13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • NADH pyrophosphatase zinc ribbon domain
  • NADH pyrophosphatase-like rudimentary NUDIX domain
  • NUDIX domain
  • pyrophosphatase
  • nucleotide diphosphatase
  • enzyme
  • NUDIX hydrolase superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • EGLN
  • BMP7
  • dimethyl n-oxalyl-glycine
  • MIR486
regulates
  • nucleoside
  • nitrogenous base
  • nucleotide
  • NADH
  • nicotinamide adenine dinucleotide phosphate
role in cell
  • apoptosis
  • necroptosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nudt13 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • NADH metabolic process
  • nucleobase-containing small molecule interconversion
  • NADP catabolic process

Cellular Component

Where in the cell the gene product is active
  • mitochondrial matrix
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • NAD+ diphosphatase activity
  • NADH pyrophosphatase activity
  • metal ion binding
  • pyrophosphatase activity

Gene-Specific Assays for Results You Can Trust

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