TMC4 Gene Summary [Human]
Predicted to enable mechanosensitive ion channel activity. Predicted to be involved in ion transmembrane transport. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | TMC4 |
| Official Name | transmembrane channel like 4 [Source:HGNC Symbol;Acc:HGNC:22998] |
| Ensembl ID | ENSG00000167608 |
| Bio databases IDs | |
| Aliases | transmembrane channel like 4 |
| Synonyms | LOC100909619, Tmc4b, transmembrane channel-like 4, transmembrane channel-like gene family 4 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMC4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Calcium-activated chloride channel
- protein binding
- voltage-gated chloride channel
- ion channel
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMC4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ion transmembrane transport
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- mechanically-gated ion channel activity