LYPD3 Gene Summary [Human]

Predicted to enable laminin binding activity. Predicted to act upstream of or within cell-matrix adhesion. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
LYPD3
Official Name
LY6/PLAUR domain containing 3 [Source:HGNC Symbol;Acc:HGNC:24880]
Ensembl ID
ENSG00000124466
Bio databases IDs NCBI: 27076 Ensembl: ENSG00000124466
Aliases LY6/PLAUR domain containing 3
Synonyms 2310061G07Rik, C4.4A, LY6/PLAUR domain containing 3
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LYPD3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • laminin binding
  • TFP

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • Laminin (complex)
role in cell
  • binding
  • migration
  • adhesion
  • motility

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • Extracellular Space
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human LYPD3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell-matrix adhesion
  • negative regulation of smooth muscle cell apoptotic process

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • laminin binding

Gene-Specific Assays for Results You Can Trust

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