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This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is predominantly expressed in the testis and in mouse, tektin 1 mRNA was localized to the spermatocytes and round spermatids in the seminiferous tubules, indicating that it may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TEKT1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
protein binding
Tektin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
Cytoplasm
microtubule cytoskeleton
axonemes
sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TEKT1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
cilium morphogenesis
cilium movement involved in cell motility
Cellular Component
Where in the cell the gene product is active
nucleus
motile cilium
microtubule cytoskeleton
axonemal microtubule
Molecular Function
What the gene product does at the molecular level
protein binding
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