Tekt1 Gene Summary [Mouse]
Involved in flagellated sperm motility. Located in microtubule cytoskeleton. Is active in axonemal A tubule inner sheath and sperm flagellum. Is expressed in several structures, including brain; lung; sensory organ; and testis. Orthologous to human TEKT1 (tektin 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tekt1 |
| Official Name | tektin 1 [Source:MGI Symbol;Acc:MGI:1333819] |
| Ensembl ID | ENSMUSG00000020799 |
| Bio databases IDs | |
| Aliases | tektin 1 |
| Synonyms | MT14, tektin 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tekt1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Tektin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- axonemes
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tekt1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- cilium movement involved in cell motility
Cellular Component
Where in the cell the gene product is active
- nucleus
- motile cilium
- microtubule cytoskeleton
- axonemal microtubule
Molecular Function
What the gene product does at the molecular level
- protein binding