RAB24 Gene Summary [Human]
RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009]
Details
| Type | Retained Intron |
| Official Symbol | RAB24 |
| Official Name | RAB24, member RAS oncogene family [Source:HGNC Symbol;Acc:HGNC:9765] |
| Ensembl ID | ENSG00000169228 |
| Bio databases IDs | |
| Aliases | RAB24, member RAS oncogene family |
| Synonyms | 6530406O07RIK, RAB24, member RAS oncogene family |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RAB24 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- small GTP-binding protein domain
- Small GTPase of the Ras superfamily (ill-defined subfamily)
- Ras family
- small monomeric GTPase
- Rab subfamily of small GTPases
- protein binding
- Ras of Complex, Roc, domain of DAPkinase
- Rho (Ras homology) subfamily of Ras-like small GTPases
- P-loop containing Nucleoside Triphosphate Hydrolases
- Ras subfamily of RAS small GTPases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- soluble fraction
- perinuclear region
- Plasma Membrane
- Endoplasmic Reticulum
- Mitochondria
- secretory granule membrane
- cytosol
- autophagic vacuoles
- late endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RAB24 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- autophagy
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- secretory granule membrane
- endomembrane system
- cytosol
- autophagic vacuole
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- GTPase activity