Mxd3 Gene Summary [Rat]

RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).[supplied by OMIM, Aug 2009]

Details

Type
Protein Coding
Official Symbol
Mxd3
Official Name
Max dimerization protein 3 [Source:RGD Symbol;Acc:628624]
Ensembl ID
ENSRNOG00000016539
Bio databases IDs NCBI: 361208 NCBI: 252915 Ensembl: ENSRNOG00000016539
Aliases Max dimerization protein 3
Synonyms 6530406O07RIK, RAB24, member RAS oncogene family
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mxd3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • small GTP-binding protein domain
  • Small GTPase of the Ras superfamily (ill-defined subfamily)
  • Ras family
  • small monomeric GTPase
  • Rab subfamily of small GTPases
  • protein binding
  • Ras of Complex, Roc, domain of DAPkinase
  • Rho (Ras homology) subfamily of Ras-like small GTPases
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • Ras subfamily of RAS small GTPases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Waldenström macroglobulinemia
regulated by
  • lipopolysaccharide
  • ETV6-RUNX1
  • F. tularensis Schu4
  • HSPG2
  • BRD2
  • prednisolone
  • topotecan
role in cell
  • formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • soluble fraction
  • perinuclear region
  • Plasma Membrane
  • Endoplasmic Reticulum
  • Mitochondria
  • secretory granule membrane
  • cytosol
  • autophagic vacuoles
  • late endosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mxd3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • autophagy
  • intracellular protein transport

Cellular Component

Where in the cell the gene product is active
  • secretory granule membrane
  • endomembrane system
  • cytosol
  • autophagic vacuole
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • protein binding
  • GTPase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.