RNASE6 Gene Summary [Human]
The protein encoded by this gene is a member of the ribonuclease A superfamily and functions in the urinary tract. The protein has broad-spectrum antimicrobial activity against pathogenic bacteria. [provided by RefSeq, Nov 2014]
Details
| Type | Protein Coding |
| Official Symbol | RNASE6 |
| Official Name | ribonuclease A family member k6 [Source:HGNC Symbol;Acc:HGNC:10048] |
| Ensembl ID | ENSG00000169413 |
| Bio databases IDs | |
| Aliases | ribonuclease A family member k6, RNase k6 |
| Synonyms | 9530043P15RIK, BB119466, LOC103694852, RAD1, ribonuclease A family member 6, ribonuclease, RNase A family, 6, RNasek6, RNS6 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RNASE6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribonuclease
- enzyme
- RNase_A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RNASE6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response to Gram-negative bacterium
- innate immune response
- defense response to virus
- antibacterial humoral response
- defense response
- defense response to Gram-positive bacterium
- RNA catabolic process
Cellular Component
Where in the cell the gene product is active
- extracellular space
- cytoplasmic vesicle
- extracellular region
- lysosome
Molecular Function
What the gene product does at the molecular level
- nucleic acid binding
- endonuclease activity
- ribonuclease activity