RBKS Gene Summary [Human]
This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Details
| Type | Protein Coding |
| Official Symbol | RBKS |
| Official Name | ribokinase [Source:HGNC Symbol;Acc:HGNC:30325] |
| Ensembl ID | ENSG00000171174 |
| Bio databases IDs | |
| Aliases | ribokinase |
| Synonyms | 5230400M11Rik, RBSK, ribokinase, RK |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RBKS often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- ribokinase_pfkB_like
- ribokinase
- protein binding
- pfkB family carbohydrate kinase
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RBKS gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- pentose-phosphate shunt
- carbohydrate phosphorylation
- D-ribose catabolic process
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- identical protein binding
- protein binding
- metal ion binding
- ribokinase activity