CDC42BPG Gene Summary [Human]
Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in protein phosphorylation. Located in cell leading edge; centriolar satellite; and cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CDC42BPG |
| Official Name | CDC42 binding protein kinase gamma [Source:HGNC Symbol;Acc:HGNC:29829] |
| Ensembl ID | ENSG00000171219 |
| Bio databases IDs | |
| Aliases | CDC42 binding protein kinase gamma |
| Synonyms | CDC42 binding protein kinase gamma, CDC42 binding protein kinase γ, DMPK2, HSMDPKIN, KAPPA-200, MRCKG, MRCKgamma, RGD1307260, κ-200 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CDC42BPG often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein serine/threonine kinase
- Autophagy protein 16 (ATG16)
- ATP binding
- Protein kinase domain
- Tropomyosin
- Extension to Ser/Thr-type protein kinases
- protein kinase C conserved region 1 (C1 domain) superfamily
- PH domain
- Tyrosine kinase, catalytic domain
- Crescentin protein
- TPR/MLP1/MLP2-like protein
- Protein kinase (unclassified specificity)
- Protein kinase C terminal domain
- Protein tyrosine and serine/threonine kinase
- CNH domain
- protein binding
- DMPK coiled coil domain like
- Pleckstrin homology-like domain
- magnesium ion binding
- Calcium binding and coiled-coil domain (CALCOCO1) like
- kinase
- Serine/Threonine protein kinases, catalytic domain
- Fez1
- Protein Kinases, catalytic domain
- Trichohyalin-plectin-homology domain
- Intermediate filament protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
- cytosol
- cell membrane leading edge
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CDC42BPG gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- actomyosin structure organization
- protein phosphorylation
- actin cytoskeleton organization
- peptidyl-threonine phosphorylation
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- cytoplasm
- cell leading edge
- centriolar satellite
- cytosol
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- ATP binding
- protein binding
- protein serine/threonine kinase activity