LURAP1 Gene Summary [Human]
Involved in positive regulation of I-kappaB kinase/NF-kappaB signaling and positive regulation of cytokine production. Located in cytosol and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | LURAP1 |
| Official Name | leucine rich adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:32327] |
| Ensembl ID | ENSG00000171357 |
| Bio databases IDs | |
| Aliases | leucine rich adaptor protein 1, leucine repeat adaptor protein 35a |
| Synonyms | 1520402A15Rik, C1orf190, leucine rich adaptor protein 1, LRAP35a, LRP35A, RGD1566001 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LURAP1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Leucine rich adaptor protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- actin cytoskeleton
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LURAP1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- positive regulation of cytokine production
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- intracellular membrane-bounded organelle
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding