RSL1D1 Gene Summary [Human]
Enables mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Involved in regulation of apoptotic process and regulation of cellular senescence. Acts upstream of or within regulation of protein localization. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RSL1D1 |
| Official Name | ribosomal L1 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:24534] |
| Ensembl ID | ENSG00000171490 |
| Bio databases IDs | |
| Aliases | ribosomal L1 domain containing 1 |
| Synonyms | 2410005K20Rik, Ac1158, CATX11, CSIG, DKFZP564M182, L12, PBK1, ribosomal L1 domain containing 1, Rsl1d1l1, UTP30, YH77E09 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RSL1D1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ribosomal_L1
- mRNA 3' UTR binding
- mRNA 5' UTR binding
- Ribosomal protein L1p/L10e family
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- infection by HIV-1
- colorectal cancer
- colon adenocarcinoma
- colon epithelial cancer
- organismal death
- idiopathic scoliosis
- colorectal carcinomagenesis
- rectal adenocarcinoma
- rectum cancer
role in cell
- apoptosis
- cell viability
- growth
- proliferation
- invasion by
- G1 phase
- binding in
- ubiquitination in
- replication in
- processing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- cilia
- cytosol
- chromosome
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RSL1D1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
- regulation of protein localization
- osteoblast differentiation
- regulation of apoptotic process
- regulation of cellular senescence
Cellular Component
Where in the cell the gene product is active
- membrane
- chromosome
- nucleolus
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- mRNA 5'-UTR binding
- cadherin binding
- mRNA 3'-UTR binding