MFSD4B Gene Summary [Human]

Predicted to enable glucose transmembrane transporter activity. Predicted to be involved in glucose transmembrane transport and sodium ion transport. Predicted to be located in apical plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MFSD4B
Official Name
major facilitator superfamily domain containing 4B [Source:HGNC Symbol;Acc:HGNC:21053]
Ensembl ID
ENSG00000173214
Bio databases IDs NCBI: 91749 Ensembl: ENSG00000173214
Aliases major facilitator superfamily domain containing 4B
Synonyms KIAA1919, major facilitator superfamily domain containing 4B, NaGLT1, SLC60A2
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MFSD4B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Major Facilitator Superfamily
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • psoriatic arthritis
  • psoriasis
  • male pattern hair loss
  • cannabis dependence

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MFSD4B gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sodium ion transport

Cellular Component

Where in the cell the gene product is active
  • apical plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • symporter activity
  • glucose transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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