NAA20 Gene Summary [Human]
NAT5 is a component of N-acetyltransferase complex B (NatB). Human NatB performs cotranslational N(alpha)-terminal acetylation of methionine residues when they are followed by asparagine (Starheim et al., 2008 [PubMed 18570629]).[supplied by OMIM, Apr 2009]
Details
| Type | Protein Coding |
| Official Symbol | NAA20 |
| Official Name | N-alpha-acetyltransferase 20, NatB catalytic subunit [Source:HGNC Symbol;Acc:HGNC:15908] |
| Ensembl ID | ENSG00000173418 |
| Bio databases IDs | |
| Aliases | N-alpha-acetyltransferase 20, NatB catalytic subunit, N-acetyltransferase 3 homolog (S. cerevisiae) |
| Synonyms | 1500004D14RIK, 2900026I01Rik, ARD1, D2Ertd186e, dJ1002M8.1, MRT73, N-alpha-acetyltransferase 20, NatB catalytic subunit, N(alpha)-acetyltransferase 20, NatB catalytic subunit, NAT3, NAT3P, NAT5, NAT5P, N-α-acetyltransferase 20, NatB catalytic subunit, N(α)-acetyltransferase 20, NatB catalytic subunit |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NAA20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Acetyltransferase (GNAT) family
- NAT_SF
- Acetyltransferase (GNAT) domain
- enzyme
- protein binding
- ribosomal-protein-alanine acetyltransferase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- cytosol
- cytoplasmic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NAA20 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- N-terminal peptidyl-aspartic acid acetylation
- N-terminal peptidyl-glutamine acetylation
- N-terminal peptidyl-methionine acetylation
- N-terminal peptidyl-glutamic acid acetylation
- N-terminal protein amino acid acetylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- NatB complex
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding
- peptide alpha-N-acetyltransferase activity