NAA25 Gene Summary [Human]
This gene encodes the auxiliary subunit of the heteromeric N-terminal acetyltransferase B complex. This complex acetylates methionine residues that are followed by acidic or asparagine residues.[provided by RefSeq, Mar 2010]
Details
| Type | Protein Coding |
| Official Symbol | NAA25 |
| Official Name | N-alpha-acetyltransferase 25, NatB auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:25783] |
| Ensembl ID | ENSG00000111300 |
| Bio databases IDs | |
| Aliases | N-alpha-acetyltransferase 25, NatB auxiliary subunit |
| Synonyms | 4833422K13Rik, A630046C11, AI450868, C12orf30, C330023M02Rik, FLJ13089, LRRGT00164, MDM20, N-alpha-acetyltransferase 25, NatB auxiliary subunit, N(alpha)-acetyltransferase 25, NatB auxiliary subunit, NAP1, N-α-acetyltransferase 25, NatB auxiliary subunit, N(α)-acetyltransferase 25, NatB auxiliary subunit, RGD1305685 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human NAA25 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- N-acetyltransferase B complex (NatB) non catalytic subunit
- protein binding
- tetratricopeptide repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- stroke
- major depression
- colorectal cancer
- breast carcinoma
- coronary artery disease
- non-small cell lung carcinoma
- non-small cell lung cancer
- gout
- hypothyroidism
- myocardial infarction
regulated by
- RYR1
- Ebna-LP
- B lymphocytes
- Ebna2
role in cell
- migration
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human NAA25 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- N-terminal peptidyl-methionine acetylation
Cellular Component
Where in the cell the gene product is active
- NatB complex
- cytoplasm
- cytosol
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein binding