MICOS10 Gene Summary [Human]
Predicted to be involved in inner mitochondrial membrane organization. Located in mitochondrion. Part of MIB complex; MICOS complex; and SAM complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | MICOS10 |
| Official Name | mitochondrial contact site and cristae organizing system subunit 10 [Source:HGNC Symbol;Acc:HGNC:32068] |
| Ensembl ID | ENSG00000173436 |
| Bio databases IDs | |
| Aliases | mitochondrial contact site and cristae organizing system subunit 10 |
| Synonyms | 2310028O11Rik, C1orf151, Mic10, MINOS1, MIO10, mitochondrial contact site and cristae organizing system subunit 10, RGD1560187 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MICOS10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Domain of unknown function (DUF543)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- thyroid disease
- hypothyroidism
- hyperthyroidism
- vascular dementia
- goiter
- multinodular goiter
- thyrotoxicosis
- nontoxic goiter
regulates
role in cell
- formation
- coregulation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human MICOS10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cristae formation
- inner mitochondrial membrane organization
Cellular Component
Where in the cell the gene product is active
- mitochondrial crista junction
- mitochondrion
- mitochondrial sorting and assembly machinery complex
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding