RBM4B Gene Summary [Human]

Enables RNA binding activity. Predicted to be involved in entrainment of circadian clock by photoperiod; mRNA splicing, via spliceosome; and regulation of gene expression. Predicted to act upstream of or within positive regulation of gene expression. Located in cytosol and nucleoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
RBM4B
Official Name
RNA binding motif protein 4B [Source:HGNC Symbol;Acc:HGNC:28842]
Ensembl ID
ENSG00000173914
Bio databases IDs NCBI: 83759 Ensembl: ENSG00000173914
Aliases RNA binding motif protein 4B
Synonyms MGC10871, RBM30, RBM4L, RNA binding motif protein 4B, ZCCHC15, ZCCHC21B, ZCRB3B
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RBM4B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc knuckle
  • zinc finger
  • RNA recognition motif (RRM) superfamily
  • RNA recognition motif
  • protein binding
  • Occluded RNA-recognition motif

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insomnia
  • ductal breast cancer
  • ductal breast carcinoma
regulated by
role in cell
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nucleoplasm
  • nucleoli
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human RBM4B gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of translation
  • circadian regulation of gene expression
  • positive regulation of gene expression
  • entrainment of circadian clock by photoperiod
  • circadian rhythm
  • nuclear mRNA splicing, via spliceosome

Cellular Component

Where in the cell the gene product is active
  • nuclear speck
  • cytosol
  • macromolecular complex
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • zinc ion binding
  • protein binding
  • RNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.