REP15 Gene Summary [Human]
The protein encoded by this intronless gene interacts with GTP-bound Rab15 and is involved in recycling of transferrin receptor from the endocytic recycling compartment to the cell surface. [provided by RefSeq, Sep 2016]
Details
| Type | Protein Coding |
| Official Symbol | REP15 |
| Official Name | RAB15 effector protein [Source:HGNC Symbol;Acc:HGNC:33748] |
| Ensembl ID | ENSG00000174236 |
| Bio databases IDs | |
| Aliases | RAB15 effector protein |
| Synonyms | 2210417D09Rik, RAB15 effector protein, RAB15EP, RGD1562899 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human REP15 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rab15 effector
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- endosomal membrane
- recycling endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human REP15 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transferrin transport
- receptor recycling
Cellular Component
Where in the cell the gene product is active
- early endosome membrane
- perinuclear region of cytoplasm
- endosome membrane
- recycling endosome
Molecular Function
What the gene product does at the molecular level
- protein binding