GDAP2 Gene Summary [Human]
Predicted to act upstream of or within response to retinoic acid. Located in lysosomal membrane. Implicated in autosomal recessive spinocerebellar ataxia 27. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | GDAP2 |
| Official Name | ganglioside induced differentiation associated protein 2 [Source:HGNC Symbol;Acc:HGNC:18010] |
| Ensembl ID | ENSG00000196505 |
| Bio databases IDs | |
| Aliases | ganglioside induced differentiation associated protein 2 |
| Synonyms | D3Ertd801e, ganglioside-induced differentiation-associated-protein 2, MACROD3, SCAR27 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GDAP2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- macro domain
- Domain in homologues of a S
- Divergent CRAL/TRIO domain
- macrodomain superfamily
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GDAP2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- response to retinoic acid
Cellular Component
Where in the cell the gene product is active
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding