TMPRSS7 Gene Summary [Human]

Predicted to enable serine-type peptidase activity. Predicted to be involved in proteolysis. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
TMPRSS7
Official Name
transmembrane serine protease 7 [Source:HGNC Symbol;Acc:HGNC:30846]
Ensembl ID
ENSG00000176040
Bio databases IDs NCBI: 344805 Ensembl: ENSG00000176040
Aliases transmembrane serine protease 7, matriptase-3
Synonyms B230219I23Rik, Gm1748, transmembrane serine protease 7
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMPRSS7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • trypsin
  • Tryp_SPc
  • CUB
  • serine-type peptidase
  • peptidase
  • LDLa
  • SEA domain
  • protein binding

Pathways

Biological processes and signaling networks where the TMPRSS7 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • endometriosis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TMPRSS7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • serine-type endopeptidase activity
  • serine-type peptidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.