C5orf46 Gene Summary [Human]
Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | C5orf46 |
| Official Name | chromosome 5 open reading frame 46 [Source:HGNC Symbol;Acc:HGNC:33768] |
| Ensembl ID | ENSG00000178776 |
| Bio databases IDs | |
| Aliases | chromosome 5 open reading frame 46, skin and saliva secreted protein 1 |
| Synonyms | AP-64, C18h5orf46, chromosome 5 open reading frame 46, Gm94, predicted gene 94, RGD1563060, similar to human chromosome 5 open reading frame 46, SSSP1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human C5orf46 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Domain of unknown function (DUF4576)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- liver cancer
- epithelial cancer
- renal clear cell adenocarcinoma
- hepatocellular carcinoma
- urothelial bladder carcinoma
- renal clear cell cancer
- transitional cell bladder cancer
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
- varicocele
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human C5orf46 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
Molecular Function
What the gene product does at the molecular level
- protein binding