FAM210B Gene Summary [Human]
Involved in cellular response to estradiol stimulus and positive regulation of erythrocyte differentiation. Located in mitochondrial outer membrane. Is intrinsic component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | FAM210B |
| Official Name | family with sequence similarity 210 member B [Source:HGNC Symbol;Acc:HGNC:16102] |
| Ensembl ID | ENSG00000124098 |
| Bio databases IDs | |
| Aliases | family with sequence similarity 210 member B, hypothetical protein LOC116151 |
| Synonyms | 2010011I20Rik, 5A3, C20orf108, dJ1167H4.1, family with sequence similarity 210 member B, family with sequence similarity 210, member B, RGD1311378 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FAM210B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- FAM210A/B-like domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- colorectal cancer
- lung adenocarcinoma formation
- EGFR mutation positive adenocarcinoma of the lung
- EGFR mutation positive non-small cell lung cancer
- EGFR expression positive non-squamous non-small cell lung cancer
regulates
- reactive oxygen species
- Immunoglobulin
role in cell
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cellular membrane
- Mitochondria
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human FAM210B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to estradiol stimulus
- positive regulation of erythrocyte differentiation
- erythrocyte maturation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- membrane
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- protein binding