GPR62 Gene Summary [Human]
Enables arrestin family protein binding activity. Involved in G protein-coupled receptor signaling pathway; inositol phosphate-mediated signaling; and positive regulation of cAMP-mediated signaling. Located in endosome and plasma membrane. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | GPR62 |
| Official Name | G protein-coupled receptor 62 [Source:HGNC Symbol;Acc:HGNC:13301] |
| Ensembl ID | ENSG00000180929 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 62 |
| Synonyms | 4933402E03RIK, GPCR8, G protein-coupled receptor 62, KPG 005, RGD1560166 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPR62 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- 7 transmembrane receptor (rhodopsin family)
- protein binding
- identical protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the GPR62 gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GPR62 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of calcium-mediated signaling
- G-protein coupled receptor signaling pathway
- G-protein coupled receptor signaling in absence of ligand
Cellular Component
Where in the cell the gene product is active
- endosome
- receptor complex
- endosome membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- identical protein binding
- protein binding