ZNF101 Gene Summary [Human]

Zinc finger proteins (ZNFs), such as ZNF101, bind nucleic acids and perform many key functions, the most important of which is regulating transcription (summary by Bellefroid et al., 1993 [PubMed 8467795]). See ZNF91 (MIM 603971) for general information on ZNFs.[supplied by OMIM, Nov 2010]

Details

Type
Protein Coding
Official Symbol
ZNF101
Official Name
zinc finger protein 101 [Source:HGNC Symbol;Acc:HGNC:12881]
Ensembl ID
ENSG00000181896
Bio databases IDs NCBI: 94039 Ensembl: ENSG00000181896
Aliases zinc finger protein 101
Synonyms HZF12, zinc finger protein 101
Species
Human, Homo sapiens

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ZNF101 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • transcription regulator
  • Zinc-finger double domain
  • protein binding
  • KRAB (Kruppel-associated box) domain -A box

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • nonalcoholic fatty liver disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human ZNF101 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • metal ion binding
  • RNA polymerase II regulatory region sequence-specific DNA binding
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

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