IGSF5 Gene Summary [Human]
Predicted to enable PDZ domain binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in apical plasma membrane. Predicted to be integral component of membrane. Predicted to be active in bicellular tight junction and cell surface. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | IGSF5 |
| Official Name | immunoglobulin superfamily member 5 [Source:HGNC Symbol;Acc:HGNC:5952] |
| Ensembl ID | ENSG00000183067 |
| Bio databases IDs | |
| Aliases | immunoglobulin superfamily member 5, junctional adhesion molecule 4 |
| Synonyms | 2010003D20Rik, GSF5, immunoglobulin superfamily member 5, immunoglobulin superfamily, member 5, JAM4, JCAM, LOC102724786 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IGSF5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- immunoglobulin domain
- Immunoglobulin like
- Immunoglobulin I-set domain
- protein binding
- PDZ-domain binding
Pathways
Biological processes and signaling networks where the IGSF5 gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- tight junctions
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IGSF5 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- tight junction
- apical plasma membrane
- cell surface