GPR1 Gene Summary [Human]
Enables adipokinetic hormone binding activity and adipokinetic hormone receptor activity. Predicted to be involved in glucose homeostasis and neuropeptide signaling pathway. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | GPR1 |
| Official Name | G protein-coupled receptor 1 [Source:HGNC Symbol;Acc:HGNC:4463] |
| Ensembl ID | ENSG00000183671 |
| Bio databases IDs | |
| Aliases | G protein-coupled receptor 1, chemerin chemokine-like receptor 2 |
| Synonyms | chemerin chemokine-like receptor 2, GPR1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GPR1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- extracellular domain
- Cholecystokinin A receptor, N-terminal
- 7 transmembrane receptor (rhodopsin family)
- protein-hormone receptor
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
- polypeptide hormone binding
Pathways
Biological processes and signaling networks where the GPR1 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- intracellular membrane-bounded organelle
- cellular membrane
- nucleoplasm
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GPR1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- G-protein coupled receptor signaling pathway
- glucose homeostasis
Cellular Component
Where in the cell the gene product is active
- intracellular membrane-bounded organelle
- neuron projection
- plasma membrane
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor activity
- neuropeptide binding
- adipokinetic hormone receptor activity
- protein binding
- adipokinetic hormone binding