DGAT2L6 Gene Summary [Human]

This gene is a member of the diacylglycerol acyltransferase 2 family. The encoded protein is a putative acyltransferase and is most likely involved in the synthesis of di- or triacylglycerol, however its substrate specificity is currently unknown. [provided by RefSeq, Feb 2015]

Details

Type
Protein Coding
Official Symbol
DGAT2L6
Official Name
diacylglycerol O-acyltransferase 2 like 6 [Source:HGNC Symbol;Acc:HGNC:23250]
Ensembl ID
ENSG00000184210
Bio databases IDs NCBI: 347516 Ensembl: ENSG00000184210
Aliases diacylglycerol O-acyltransferase 2 like 6
Synonyms 9930021F22Rik, DC3, diacylglycerol O-acyltransferase 2-like 6, LOC684239
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DGAT2L6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis
  • diacylglycerol O-acyltransferase
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • COVID-19
  • idiopathic scoliosis
regulates
  • triacylglycerol
  • monoacylglycerol

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • endoplasmic reticulum membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human DGAT2L6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • acylglycerol acyl-chain remodeling
  • lipid metabolic process
  • monoacylglycerol biosynthetic process

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • O-acyltransferase activity
  • diacylglycerol O-acyltransferase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.