TMEM143 Gene Summary [Human]
Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | TMEM143 |
| Official Name | transmembrane protein 143 [Source:HGNC Symbol;Acc:HGNC:25603] |
| Ensembl ID | ENSG00000161558 |
| Bio databases IDs | |
| Aliases | transmembrane protein 143 |
| Synonyms | 2310076O21Rik, RGD1305013, transmembrane protein 143 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM143 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein of unknown function (DUF3754)
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMEM143 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- membrane
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- protein binding