LRRC26 Gene Summary [Human]
Enables potassium channel activator activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Involved in positive regulation of voltage-gated potassium channel activity and potassium ion transmembrane transport. Is integral component of plasma membrane. Part of voltage-gated potassium channel complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | LRRC26 |
| Official Name | leucine rich repeat containing 26 [Source:HGNC Symbol;Acc:HGNC:31409] |
| Ensembl ID | ENSG00000184709 |
| Bio databases IDs | |
| Aliases | leucine rich repeat containing 26 |
| Synonyms | bA350O14.10, CAPC, leucine rich repeat containing 26, RGD1308398 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LRRC26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Leucine-rich repeats, outliers
- Leucine-rich repeats, typical (most populated) subfamily
- channel regulator
- voltage-gated potassium channel
- potassium channel regulator
- Leucine rich repeat
- ion channel binding
- Leucine rich repeat C-terminal domain
- protein binding
- ion channel
Pathways
Biological processes and signaling networks where the LRRC26 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell periphery
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LRRC26 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- potassium ion transmembrane transport
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytoskeleton
- cytoplasm
- voltage-gated potassium channel complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- voltage-gated potassium channel activity
- protein binding
- ion channel binding
- potassium channel regulator activity