LCN12 Gene Summary [Human]
Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]
Details
| Type | Processed Transcript |
| Official Symbol | LCN12 |
| Official Name | lipocalin 12 [Source:HGNC Symbol;Acc:HGNC:28733] |
| Ensembl ID | ENSG00000184925 |
| Bio databases IDs | |
| Aliases | lipocalin 12 |
| Synonyms | 9230102M18Rik, lipocalin 12, LOC687251 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LCN12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- binding protein
- lipocalin/cytosolic fatty acid-binding protein family
- retinoid binding
- Lipocalin / cytosolic fatty-acid binding protein family
- transporter
Pathways
Biological processes and signaling networks where the LCN12 gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LCN12 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular region
Molecular Function
What the gene product does at the molecular level
- retinoic acid binding