MANEAL Gene Summary [Human]

Predicted to enable alpha-mannosidase activity. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
MANEAL
Official Name
mannosidase endo-alpha like [Source:HGNC Symbol;Acc:HGNC:26452]
Ensembl ID
ENSG00000185090
Bio databases IDs NCBI: 149175 Ensembl: ENSG00000185090
Aliases mannosidase endo-alpha like
Synonyms Baculoviral IAP repeat-containing 4, Gm50, mannosidase endo-alpha like, mannosidase, endo-alpha-like, mannosidase endo-α like, mannosidase, endo-α-like, RGD1563973
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human MANEAL often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Glycoside hydrolase families 71, 99, and related domains

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • rheumatoid arthritis
  • HER2 negative hormone receptor negative breast cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human MANEAL gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • Golgi membrane
  • Golgi apparatus

Molecular Function

What the gene product does at the molecular level
  • alpha-mannosidase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.