C6orf120 Gene Summary [Human]
This gene encodes a conserved, N-glycosylated protein that likely functions in the cellular response to endoplasmic reticulum stress. This protein is able to induce apoptosis in vitro in CD4+ T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Details
| Type | Protein Coding |
| Official Symbol | C6orf120 |
| Official Name | chromosome 6 open reading frame 120 [Source:HGNC Symbol;Acc:HGNC:21247] |
| Ensembl ID | ENSG00000185127 |
| Bio databases IDs | |
| Aliases | chromosome 6 open reading frame 120 |
| Synonyms | 1600012H06Rik, C1h6orf120, chromosome 6 open reading frame 120, RIKEN cDNA 1600012H06 gene, similar to human chromosome 6 open reading frame 120 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human C6orf120 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Putative cytokine, C6ORF120
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- azurophil granule lumen
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human C6orf120 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- apoptotic process
Cellular Component
Where in the cell the gene product is active
- extracellular region
- azurophil granule lumen