KRT79 Gene Summary [Human]

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in skeletal muscle, skin and scalp. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]

Details

Type
Retained Intron
Official Symbol
KRT79
Official Name
keratin 79 [Source:HGNC Symbol;Acc:HGNC:28930]
Ensembl ID
ENSG00000185640
Bio databases IDs NCBI: 338785 Ensembl: ENSG00000185640
Aliases keratin 79, keratin 6-like
Synonyms K6L, keratin 79, KRT6L, LOC685652
Species
Human, Homo sapiens
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KRT79 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • TPR/MLP1/MLP2-like protein
  • enzyme binding
  • protein binding
  • Intermediate filament protein
  • Keratin type II head

Pathways

Biological processes and signaling networks where the KRT79 gene in human plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • psoriasis
  • tinnitus
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human KRT79 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • keratinization
  • intermediate filament organization

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • keratin filament
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • structural constituent of epidermis
  • protein binding
  • enzyme binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.