EVI2B Gene Summary [Human]
Involved in positive regulation of granulocyte differentiation. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | EVI2B |
| Official Name | ecotropic viral integration site 2B [Source:HGNC Symbol;Acc:HGNC:3500] |
| Ensembl ID | ENSG00000185862 |
| Bio databases IDs | |
| Aliases | ecotropic viral integration site 2B |
| Synonyms | CD361, D17S376, ecotropic viral integration site 2B, EVDB, Evi-2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human EVI2B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human EVI2B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of granulocyte differentiation
- negative regulation of apoptotic process
- positive regulation of neutrophil differentiation
- regulation of stem cell division
- regulation of cell cycle
Cellular Component
Where in the cell the gene product is active
- plasma membrane