TMEM86B Gene Summary [Human]
Enables alkenylglycerophosphocholine hydrolase activity; alkenylglycerophosphoethanolamine hydrolase activity; and identical protein binding activity. Involved in ether lipid metabolic process. Located in cytoplasm and membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Retained Intron |
| Official Symbol | TMEM86B |
| Official Name | transmembrane protein 86B [Source:HGNC Symbol;Acc:HGNC:28448] |
| Ensembl ID | ENSG00000180089 |
| Bio databases IDs | |
| Aliases | transmembrane protein 86B, alkenylglycerophosphocholine hydrolase, alkenylglycerophosphoethanolamine hydrolase |
| Synonyms | C330014O21Rik, LOC684090, transmembrane protein 86B |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TMEM86B often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alkenylglycerophosphocholine hydrolase
- D-lysine 5,6-aminomutase
- enzyme
- protein binding
- ether hydrolase
- YhhN family
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Plasma Membrane
- cytosol
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TMEM86B gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- phosphatidylcholine acyl-chain remodeling
- ether lipid metabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- cytoplasm
- membrane
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- ether hydrolase activity
- alkenylglycerophosphocholine hydrolase activity
- D-lysine 5,6-aminomutase activity