CD300E Gene Summary [Human]

This gene encodes a member of the CD300 glycoprotein family of cell surface proteins expressed on myeloid cells. The protein interacts with the TYRO protein tyrosine kinase-binding protein and is thought to act as an activating receptor. [provided by RefSeq, Nov 2012]

Details

Type
Protein Coding
Official Symbol
CD300E
Official Name
CD300e molecule [Source:HGNC Symbol;Acc:HGNC:28874]
Ensembl ID
ENSG00000186407
Bio databases IDs NCBI: 342510 Ensembl: ENSG00000186407
Aliases CD300e molecule
Synonyms CD300e molecule, CD300LE, CLM-2, CMRF35-A5, IREM-2, LOC688252, PIgR-2
Species
Human, Homo sapiens
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CD300E often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • immunoglobulin domain
  • protein binding
  • Immunoglobulin V-set domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • prostaglandin E2
  • ATP-gamma-S
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human CD300E gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • immune system process

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • transmembrane signaling receptor activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

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