CD300C Gene Summary [Human]
The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | CD300C |
| Official Name | CD300c molecule [Source:HGNC Symbol;Acc:HGNC:19320] |
| Ensembl ID | ENSG00000167850 |
| Bio databases IDs | |
| Aliases | CD300c molecule |
| Synonyms | CD300C molecule, CLM-6, CMRF-35, CMRF-35A, CMRF35-A1, IGSF16, LIR, LOC105371892 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CD300C often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ig superfamily domain
- immunoglobulin domain
- transmembrane domain
- Immunoglobulin like
- protein binding
- transmembrane receptor
- Immunoglobulin V-set domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- breast cancer
- early missed abortion
- septic shock
- glioblastoma
- glioblastoma cancer
- juvenile rheumatoid arthritis
role in cell
- expression in
- response
- binding in
- transactivation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CD300C gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular defense response
- immune system process
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- transmembrane signaling receptor activity
- protein binding