FSD2 Gene Summary [Human]

This gene encodes a protein that belongs to the FN3/SPRY family of proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Details

Type
Protein Coding
Official Symbol
FSD2
Official Name
fibronectin type III and SPRY domain containing 2 [Source:HGNC Symbol;Acc:HGNC:18024]
Ensembl ID
ENSG00000186628
Bio databases IDs NCBI: 123722 Ensembl: ENSG00000186628
Aliases fibronectin type III and SPRY domain containing 2, minispryn
Synonyms 9830160G03Rik, fibronectin type III and SPRY domain containing 2, LOC123722, RGD1305167, SPRYD1
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human FSD2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • coiled-coil (CC) domain of Drosophila brain tumor (brat) and similar proteins
  • B-Box C-terminal domain
  • SPRY domain
  • FN3
  • high mobility group (HMG)-box domain superfamily
  • Purple acid Phosphatase, N-terminal domain
  • protein binding
  • Fibronectin type 3 domain
  • associated with SPRY domains
  • SPRY-associated domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • cleft lip
regulated by
  • dexamethasone

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • perinuclear region
  • Nucleus
  • sarcoplasmic reticulum

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human FSD2 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • perinuclear region of cytoplasm
  • sarcoplasmic reticulum

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.