Fsd2 Gene Summary [Mouse]
Predicted to be located in nucleus; perinuclear region of cytoplasm; and sarcoplasmic reticulum. Is expressed in hindlimb long bone and tarsus. Orthologous to human FSD2 (fibronectin type III and SPRY domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fsd2 |
| Official Name | fibronectin type III and SPRY domain containing 2 [Source:MGI Symbol;Acc:MGI:2444310] |
| Ensembl ID | ENSMUSG00000038663 |
| Bio databases IDs | |
| Aliases | fibronectin type III and SPRY domain containing 2 |
| Synonyms | 9830160G03Rik, fibronectin type III and SPRY domain containing 2, LOC123722, RGD1305167, SPRYD1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fsd2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- coiled-coil (CC) domain of Drosophila brain tumor (brat) and similar proteins
- B-Box C-terminal domain
- SPRY domain
- FN3
- high mobility group (HMG)-box domain superfamily
- Purple acid Phosphatase, N-terminal domain
- protein binding
- Fibronectin type 3 domain
- associated with SPRY domains
- SPRY-associated domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- perinuclear region
- Nucleus
- sarcoplasmic reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fsd2 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
- perinuclear region of cytoplasm
- sarcoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- protein binding