POTEE Gene Summary [Human]
Involved in retina homeostasis and substantia nigra development. Located in blood microparticle and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | POTEE |
| Official Name | POTE ankyrin domain family member E [Source:HGNC Symbol;Acc:HGNC:33895] |
| Ensembl ID | ENSG00000188219 |
| Bio databases IDs | |
| Aliases | POTE ankyrin domain family member E, cancer/testis antigen family 104, member 2 |
| Synonyms | A26C1, A26C1A, CT104.2, POTE-2, POTE2gamma, POTE ankyrin domain family member E |
| Species | Human, Homo sapiens |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human POTEE often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ankyrin repeats (many copies)
- Actin
- Ankyrin repeats (3 copies)
- protein binding
- Ankyrin repeat
- ASKHA_ATPase-like
- ankyrin repeats
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human POTEE gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell motility
- axonogenesis
- substantia nigra development
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
- NuA4 histone acetyltransferase complex
- cytoplasm
- blood microparticle
- membrane
- actin cytoskeleton
- synapse
- actin filament
- axon
Molecular Function
What the gene product does at the molecular level
- protein kinase binding